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An expeditious route to the germacranes. Total synthesis of (.+-.)-acoragermacrone and (.+-.)-preisocalamendiol

โœ Scribed by Still, W. Clark


Book ID
126790788
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
298 KB
Volume
99
Category
Article
ISSN
0002-7863

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An expeditious route to the synthesis of
โœ Nicole C.R. van Straten; Gijsbert A. van der Marel; Jacques H. van Boom ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 851 KB

Glycosylation of 1,2-O-isopropylidene-5-O-tert-butyldiphenylsilyl-o~-D-ribofuranose (8) with ethyl 3,4,6-tri-O-acetyl-2-O-benzyl-l-thio-~/l~-D-glucopyranoside (7) under the agency of Niodosuccinimide and trifluoromethanesulfonic acid afforded Gt-linked dimer 10 in 95% yield. Acetylation of 13, obtai