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An expeditious one-pot synthesis of substituted phenylazetidin-2-ones in the presence of zeolite

โœ Scribed by Ramakanth Pagadala; Jyotsna S. Meshram; Himani N. Chopde; Venkateshwarlu Jetti; V. Udayini

Book ID
102343233
Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
148 KB
Volume
48
Category
Article
ISSN
0022-152X

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โœฆ Synopsis

Abstract

In this study, oneโ€pot rapid and efficient series of phenylazetidinโ€2โ€ones were synthesized from N,Nโ€dimethylaminobenzaldehyde, different substituted aromatic amines and phenylacetyl chloride in the presence of zeolite catalyst under microwave irradiation. We also reported schiff bases (1aโ€“j) by classical and conventional microwave technique. The titled compounds are evaluated for their antimicrobial properties. The activities are due to C๏ฃพO, C๏ฃฟN, linkages in 2โ€azetidinones. All the compounds have shown comparable antibacterial activities. J. Heterocyclic Chem., (2011).

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