An Expeditious, Non-Iterative, and Asymmetric Synthesis of 3,5,7,9,11,13,15-Heptahydroxypentadecanals
✍ Scribed by Sandrine Gerber-Lemaire; Pierre Vogel
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 155 KB
- Volume
- 2003
- Category
- Article
- ISSN
- 1434-193X
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📜 SIMILAR VOLUMES
## Abstract The synthesis of the title compounds (**1** and **3**) is described. Some of the compounds prepared were found to be active against a number of pathogenic microorganisms __in vitro.__ Structure‐activity relationship is briefly discussed.
## Abstract The 2,2′‐methylenebis[furan] (**1**) was converted to 1‐{(4__R__,6__S__))‐6‐[(2__R__)‐2,4‐dihydroxybutyl]‐2,2‐dimethyl‐1,3‐dioxan‐4‐yl}‐3‐[(2__R__,4__R__)‐tetrahydro‐4,6‐dihydroxy‐2__H__‐pyran‐2‐yl)propan‐2‐one ((+)‐**18**) and its (4__S__)‐epimer (−)‐**19** with high stereo‐ and enanti