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An expeditious approach to the synthesis of chiral butadienyl alcohols

✍ Scribed by J.S. Yadva; D Srinivas; T Shekharam

Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
228 KB
Volume
35
Category
Article
ISSN
0040-4039

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✦ Synopsis

ANtZSCt:

A highly reqioseZectrive redu&ioz~ of epoxy allylic alcohols to chiral butmiienyf alcohols and its application to tax01 skeleton is descxibed.

Antitumour taxoids have always been a constant challenge to organic chemists.

Among these classes of natural products, taxol' (1) occupies the prominent position not only because of its biological significance, 2 but also its structural complexities.

(l38)/86 of PL 480 (NIH) and CSIR, New Delhi.

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