𝔖 Bobbio Scriptorium
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An Expedient Route to New Spiroheterocycles: Synthesis and Structural Studies

✍ Scribed by Marlène Goubert; Isabelle Canet; Marie-Eve Sinibaldi


Book ID
102170432
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
182 KB
Volume
2006
Category
Article
ISSN
1434-193X

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An expedient route to aromatic pyrrolo[2
✍ Frédéric Fabis; Jana Sopkova-de Oliveira Santos; Sandrine Fouchet-Jolivet; Sylva 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 90 KB

## 2- Hydroxypyrrolo[2, 4 ]benzodiazepines were aromatised in refluxing thionyl chloride into 11-chloropyrrolo[2,1-c]- [1,4]benzodiazepines in high yield. This aromatic system is doubly reactive towards nucleophiles leading to rearranged products such as iminobenzoxazines and quinazolines.