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An expedient radical based approach to difluorophosphonate analogues of thionucleosides

โœ Scribed by Jean Boivin; Laure Ramos; Samir Z. Zard

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
232 KB
Volume
39
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

An expedient approach to difluorophosphonate analogues of thionucleosides of general structure 1 is described; the key step is a radical xanthate transfer chain reaction on diethyl 1.1difluoro-3-butenylphosphonate.

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