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An Expansion of CD3+CD8+CD28-NKG2A+ T-Cells Occurs in Individuals With Active Celiac Disease

✍ Scribed by Sharaiha, Reem Z. ;Wang, Zhao-Yuan ;Vlad, George ;Green, Peter H. ;Bhagat, Govind

Book ID
122108761
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
136 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Treatment with anti‐CD3 mAb modulates immune responses that cause type 1 diabetes and other diseases. CD8^+^ Tregs can be induced in vitro and in vivo by mAb. However, 1/3 of patients do not respond to drug therapy and in an equal proportion, anti‐CD3 mAb does not induce Tregs in vitro.