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An example for an underpowered study: a comment on Ginkgo biloba for mild to moderate dementia in a community setting by McCarney et al.

✍ Scribed by Professor Dr Wilhelm Gaus

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 33 KB
Volume: 24
Category: Article
ISSN: 0885-6230
DOI: 10.1002/gps.2172

No coin nor oath required. For personal study only.

✦ Synopsis

Schwabe supports a research fellowship in my unit which is unrelated to research into Ginkgo or dementia. REFERENCES Ernst E, Pittler MH. 2005. Ginkgo biloba for vascular dementia and Alzheimer's disease: updated systematic review of double-blind placebo-controlled, randomized trials. Perfusion 18: 388-392. McCarney R, Fisher P, Iliffe S, et al. 2008. Ginkgo biloba for mild to moderate dementia in a community setting: a pragmatic, random-ised, parallel-group, double-blind, placebo-controlled trial. Int J Geriatr Psychiatry, in press.

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## Abstract ## Objectives Doubt over the cost‐effectiveness of the cholinesterase inhibitors in dementia has renewed interest in alternative treatments such as Ginkgo biloba. We aimed to determine the effectiveness and the safety profile of Ginkgo biloba for treating early stage dementia in a comm