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An evaluation of the genotoxicity of the antitussive drug Dextromethorphan

✍ Scribed by Marilyn J. Aardema; Steven H. Robison; David Gatehouse; Gail Johnston


Book ID
113965277
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
174 KB
Volume
50
Category
Article
ISSN
0273-2300

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Pyrimethamine is an antimalarial drug and a known teratogenic agent. With this drug, positive and negative results have been reported by various investigators in in vivo and in vitro genotoxicity/mutagenicity assays. In this investigation the genotoxic effects of pyrimethamine (PY) were tested in mi