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An ethanol solvate of Beclomethasone dipropionate

✍ Scribed by Kuehl, Philip J. ;Carducci, Michael D. ;Myrdal, Paul B.

Book ID
104481131
Publisher
International Union of Crystallography
Year
2003
Tongue
English
Weight
640 KB
Volume
59
Category
Article
ISSN
1600-5368

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✦ Synopsis

Single-crystal X-ray study T = 170 K Mean '(C±C) = 0.005 A Ê Some non-H atoms missing Disorder in solvent or counterion R factor = 0.067 wR factor = 0.118 Data-to-parameter ratio = 18.8 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

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Single-crystal X-ray study T = 170 K Mean '(C±C) = 0.003 A Ê Some non-H atoms missing R factor = 0.044 wR factor = 0.099 Data-to-parameter ratio = 21.5 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

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The relative affinity of beclomethasone (B), bec1omethasone-17-monopropionate (1 7-BMP), beclomethasone-2 I-monopropionate (21 -BMP), and beclomethasone dipropionate (BDP) has been determined. BDP binds to the glucocorticoid receptor with about half the affinity of the potent glucocorticoid dexameth