## Abstract __ADAM12__ has recently emerged as a Candidate Cancer Gene in a comprehensive genetic analysis of human breast cancers. Three somatic mutations in ADAM12 were observed at significant frequencies in breast cancers: D301H, G479E and L792F. The first 2 of these mutations involve highly con
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
β Scribed by Hui Li, Sara Duhachek-Muggy, Yue Qi, Yan Hong, Fariba Behbod, Anna Zolkiewska
- Book ID
- 118796721
- Publisher
- Springer US
- Year
- 2012
- Tongue
- English
- Weight
- 786 KB
- Volume
- 135
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract __ADAM__ genes have been associated with cancer, with __ADAM__ expression, genomic rearrangements, and, by implication of ADAM proteins in the altered behavior found in tumor cells. In the present study, increased copy number of the __ADAM15__ gene in human breast cancer cell lines was
First published in 1943, *Vitamins and Hormones* is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial