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An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

โœ Scribed by Asseman, Chrystelle (author);Mauze, Smita (author);Leach, Michael W. (author);Coffman, Robert L. (author);Powrie, Fiona (author)


Book ID
111877669
Publisher
Rockefeller University Press
Year
1999
Tongue
English
Weight
204 KB
Volume
190
Category
Article
ISSN
0022-1007

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โœ Zhanju Liu; Karel Geboes; Hubertine Heremans; Lutgart Overbergh; Chantal Mathieu ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 559 KB

IL-12 promotes Th1 cell differentiation and cell-mediated immunity. In the present study, the potential role of IL-12 was analyzed in an experimental colitis model in scid mice reconstituted with syngeneic CD45RB high CD4 + T cells. Real-time reverse transcription-PCR studies demonstrated that IL-12