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An enzyme immunoassay design using labelled antibodies for the determination of haptens. Application to methotrexate assay

✍ Scribed by B. Ferrua; G. Milano; B. Ly; J.Y. Guennec; R. Masseyeff

Book ID
118899153
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
564 KB
Volume
60
Category
Article
ISSN
0022-1759

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The development of a group-specific immunochemical test as a new approach to screening is reported. The broadening of antibody specificity was achieved by design of td hapten part of the immunogen. We used molecular modelling to investigate the structure of the hapten and the influence of the spacer