An Enantiospecific Synthesis of the Potent Immunosuppressant FR901483

✍ Scribed by Goetz Scheffler; Hirofumi Seike; Erik J. Sorensen

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 105 KB
• Volume: 39
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/1521-3773(20001215)39:24<4593::aid-anie4593>3.0.co;2-x

✦ Synopsis

Checking the purity of the cold solid products after dissolution in CH 2 Cl 2 at À 78 8C showed in the case of 1 and 2 degrees of decomposition of up to 10 % and for the thermally more sensitive product 3 up to 30 %.