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An Enantioselective Synthesis of Deoxynojirimycin

✍ Scribed by Andrew J. Rudge; Dr. Ian Collins; Dr. Andrew B. Holmes; Dr. Raymond Baker


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
393 KB
Volume
33
Category
Article
ISSN
0044-8249

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Synthesis of Somatostatin Mimetics Based
✍ Vincent Chagnault; JΓ©rΓ΄me Lalot; Paulβ€…V. Murphy πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 355 KB

## Abstract The synthesis of novel somatostatin mimetics from 1‐deoxynojirimycin (DNJ) is described. The dipeptide mimetic, which respectively displayed the side chains of tryptophan and lysine at the nitrogen and O6 atoms of the iminosugar scaffold is a ligand (__K~i~__=3.2β€…ΞΌM) for the human somat