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An Enantioconvergent Synthesis of (R)-4-Aryloxy-1-butyne-3-ols for Prostanoid Side Chains

✍ Scribed by Martin E. Fox; Mark Jackson; Ian C. Lennon; Raymond McCague; Julian S. Parratt


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
133 KB
Volume
344
Category
Article
ISSN
1615-4150

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✍ Joannes T. M. Linders; Seid Mirsadeghi; Judith L. Flippen-Anderson; Clifford Geo 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 162 KB

## Abstract The synthesis of a series of epoxy 5‐phenylmorphans is being explored in order to determine the conformational requirements of the phenolic ring in a phenylmorphan molecule that may be needed both for binding to a specific opioid receptor and for exhibiting opioid agonist or antagonist