An eluent–jet interface for chemical ionization mass spectrometry and coupling of microcolumn liquid chromatography with electron ionization mass spectrometry

✍ Scribed by Reyer J. Dijkstra; Ben L. M. Van Baar; Charles E. Kientz; Wilfried M. A. Niessen; Udo A. Th. Brinkman

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 190 KB
• Volume: 12
• Category: Article
• ISSN: 0951-4198
• DOI: 10.1002/(sici)1097-0231(19980115)12:1<5::aid-rcm109>3.0.co;2-2

✦ Synopsis

An improved eluent-jet interface was used to combine flow-injection analysis (FIA) and micro-column liquid chromatography (LC) on-line with mass spectrometry (MS) in the electron ionization (EI) and solvent-independent chemical ionization (CI) modes. Good results were obtained for a series of pesticides and for 2-(diethylamino)ethanol (DEAE), a precursor of the chemical warfare V-agents. When using singleion monitoring, 50 pg of DEAE could be detected in the CI mode, and a linear calibration plot was obtained in the test range of 50-1000 pg. EI-MS spectra obtained in both FIA and micro-LC experiments were closely analogous to those in conventional mass spectral libraries.