Physiologically based pharmacokinetic mo
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Shweta R. Urva; Victor C. Yang; Joseph P. Balthasar
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Article
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2010
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John Wiley and Sons
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English
โ 322 KB
Antibodies directed against tumor associated antigens are being increasingly used for detection and treatment of cancers; however, there is an incomplete understanding of the physiological determinants of antibody pharmacokinetics and tumor distribution. The purpose of this study is to (a) compare t