𝔖 Bobbio Scriptorium
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An electrospray ionization mass spectrometry study of copper adducts of protonated ubiquitin

✍ Scribed by Charles Q. Jiao; Ben S. Freiser; Scott R. Carr; Carolyn J. Cassady


Book ID
103996797
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
382 KB
Volume
6
Category
Article
ISSN
1044-0305

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✦ Synopsis


A study of the addition of Cu(II) to a ubiquitin electrospray solution shows that the copper ion in the ubiquitin remains doubly charged and displaces two protons on the protonated protein molecule. This observation indicates a chelating bond between the protein and the Cu(I1) species. The addition of Cu(1) also was studied and significant intensity was observed for adducts with up to four Cu(1) species attached, with each Cu(1) bonded to one basic site on the protein.


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