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An Efficient Unnatural Base Pair for a Base-Pair-Expanded Transcription System

โœ Scribed by Mitsui, Tsuneo; Kimoto, Michiko; Harada, Yoko; Yokoyama, Shigeyuki; Hirao, Ichiro

Book ID
126282371
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
387 KB
Volume
127
Category
Article
ISSN
0002-7863

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## Abstract As part of an ongoing effort to expand the genetic alphabet for in vitro and eventual in vivo applications, we have synthesized a wide variety of predominantly hydrophobic unnatural base pairs and evaluated their replication in DNA. Collectively, the results have led us to propose that