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An Efficient Total Synthesis of Okadaic Acid

โœ Scribed by Forsyth, Craig J.; Sabes, Steven F.; Urbanek, Rebecca A.


Book ID
125545048
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
236 KB
Volume
119
Category
Article
ISSN
0002-7863

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## Abetract Three segments A, B and C for okadaic acid synthesis were coupled with each other in the order of At(BtC), the key steps of the twice couplings being between sulfone carbanions and aldehydea. After the BtC coupling, the asymmetric center C-27 was generated by a hydride reduction of the