An efficient tandem approach for the synthesis of functionalized 2-pyridone-3-carboxylic acids using three-component reaction in aqueous media
β Scribed by Mehrparvar, Saber; Balalaie, Saeed; Rabbanizadeh, Mahnaz; Ghabraie, Elmira; Rominger, Frank
- Book ID
- 125366067
- Publisher
- Springer
- Year
- 2014
- Tongue
- English
- Weight
- 494 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1381-1991
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π SIMILAR VOLUMES
Reactions of biacetyl (ΒΌ butane-2,3-dione) with (N-isocyanimino)triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and under neutral conditions to afford 3-(5-aryl-1,3,4-oxadiazol-2-yl)-3-hydroxybutan-2-one derivatives in high yields. Introduction
## Abstract Reactions of electronβpoor Ξ±βhaloketones with (__N__βisocyanimino) triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions to afford disubstituted 1,3,4βoxadiazole derivatives in high yields. Β© 2010 Wiley Periodica