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An efficient synthesis of (R)- and (S)-2-(aminomethyl)piperidine dihydrochloride

✍ Scribed by Gildas Deniau; Thomas Moraux; David O’Hagan; Alexandra M.Z. Slawin


Book ID
108284388
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
186 KB
Volume
19
Category
Article
ISSN
0957-4166

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An Efficient Synthesis of Optically Pure
✍ Daniel Obrecht; Helena Karajiannis; Christian Lehmann; Peter Schönholzer; Clive 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 German ⚖ 783 KB

An efficient synthesis of enantiomerically pure (R)and (S)-2-(aminomethyl)alanine ((R)and (S)-Ama) la and ( R ) -and (S)-2-(aminomethyl)leucine ( ( R )and (S)-Aml) l b is described (Schemes I and 2). Resolution of the racemic amino acids was achieved using L-phenylalanine cyclohexylamide (2) as chir