An efficient synthesis of quinoxaline derivatives mediated by stannous chloride
β Scribed by Da-Qing Shi; Guo-Lan Dou; Sai-Nan Ni; Jing-Wen Shi; Xiao-Yue Li
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2008
- Tongue
- English
- Weight
- 208 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0022-152X
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β¦ Synopsis
Abstract
magnified image
Various biologically important quinoxaline derivatives were efficiently synthesized in excellent yields by the reaction of 1,2βdiketones and 2βnitroaniline, benzofuroxan or 1,2βdinitrobenzene promoted by SnCl~2~2H~2~O. The role of stannous chloride is acting as both reductive agent and catalyst in this synthesis. This new method has the advantages of accessible starting materials, convenient manipulation, short reaction time and high yields.
π SIMILAR VOLUMES
## Abstract magnified image A series of quinoxaline derivatives have been synthesized in excellent yields by the condensation of 1,2βdiketones and 1,2βphenylenediamines in the presence of a catalytic amount of NbCl~5~ at room temperature in short times. J. Heterocyclic Chem., (2010).
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