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An efficient synthesis of polyoxamic acid utilizing the aryl group as the carboxyl synthon. A new approach to polyhydroxyamino acids

✍ Scribed by Fumiyoshi Matsuura; Yasumasa Hamada; Takayuki Shioiri

Book ID: 104215570
Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 327 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)75803-5

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✦ Synopsis

Abswacr: Polyoxamic acid (1). an amino acid moiety of antifungal antibiotics polyoxins, has been efficiently syntlxsized from Boc-(R)4-hydroxyphenylglycine (3) utilizing its aryl gmup as the carboxy synthon.

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