An efficient synthesis of polyhydroacridine derivatives by the three-component reaction of aldehydes, amines and dimedone in ionic liquid

✍ Scribed by Da-Qing Shi; Sai-Nan Ni; Fang-Yang; Jing-Wen Shi; Guo-Lan Dou; Xiao-Yue Li; Xiang-Shan Wang

• Publisher: Journal of Heterocyclic Chemistry
• Year: 2008
• Tongue: English
• Weight: 536 KB
• Volume: 45
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570450303

✦ Synopsis

Abstract

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In this paper the preparation of 3,3,6,6‐tetramethyl‐9,10‐diaryl‐1,2,3,4,5,6,7,8,9,10‐decahydroacridine‐1,8‐dione derivatives from aldehydes, aromatic amines and 5,5‐dimethyl‐1,3‐cyclohexanedione in 1‐n‐butyl‐3‐methylimidazolium bromide ([bmim]Br) is described. The structures of these compounds were characterized by elemental analysis, IR and ^1^H NMR spectra and further confirmed by single crystal X‐ray diffraction analysis.