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An efficient synthesis of novel deoxy phospha sugar pyrimidine nucleosides

✍ Scribed by Mitsuji Yamashita; Valluru Krishna Reddy; Putta Mallikarjuna Reddy; Yukihiro Kato; Buchammagari Haritha; Kazumitsu Suzuki; Masaki Takahashi; Tatsuo Oshikawa


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
199 KB
Volume
44
Category
Article
ISSN
0040-4039

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✦ Synopsis


An efficient method is described in the synthesis of several novel deoxy phospha sugar pyrimidine nucleosides in racemic form, analogs of normal sugar nucleosides, in high yields by treatment of (Β±)-2-aminophospholane 1-oxide with several, a-cyano-, -acetyl-, -ethoxycarbonyl-b-ethoxy-N-ethoxycarbonylacrylamides.


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