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An Efficient Synthesis of Mono and Bis-1,2,3-triazole AZT Derivatives via Copper(I)-catalyzed Cycloaddition

✍ Scribed by Jin-Wei Yuan; Ling-Bo Qu; Xiao-Lan Chen; Zhi-Bo Qu; Xiang-Qian Liu; Dian-Dian Ke

Book ID: 112120397
Publisher: Chinese Electronic Periodical Services
Year: 2011
Tongue: English
Weight: 735 KB
Volume: 58
Category: Article
ISSN: 0009-4536
DOI: 10.1002/jccs.201190053

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## Abstract A practical and efficient synthesis of triazolothiadiazepine‐1,1‐dioxide derivatives __via__ copper‐catalyzed [3+2] cycloaddition, followed by __N__‐arylation is described. The method is also applicable to the synthesis of indoline‐ and thiophene‐fused triazolothiadiazepine 1,1‐dioxide