An efficient synthesis of anti-(1R)-(+)-camphorquinone 3-oxime

✍ Scribed by Susmita Roy (née Bhattacharaya); Asit K. Chakraborti

• Book ID: 104259705
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 96 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)01307-0

✦ Synopsis

The camphor derived amino alcohol (1) is used as chiral auxiliary/reagent in various asymmetric transformations.1 Reductiontb,~2 of camphorquinone 3-oxime (2) appears to be the most common synthetic strategy lb'~2 for 1. However the poor yield for the preparation of 2 via the nitrosation 3 of camphor led to