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An Efficient Synthesis of 4-Naphthylpyrimidin-2-amine Derivatives under Solvent-Free Conditions

✍ Scribed by Liangce Rong; Honglou Ji; Sheng Xia; Shan Yin; Yanhui Shi; Shujiang Tu

Book ID: 112131790
Publisher: Journal of Heterocyclic Chemistry
Year: 2012
Tongue: English
Weight: 114 KB
Volume: 49
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.839

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## Abstract A simple, efficient and convenient one‐pot synthesis of 2,3‐dihydroquinazolin‐4(1__H__)‐one derivatives under solvent‐free and catalyst‐free conditions by the reaction of aromatic aldehydes, isatoic anhydride, and ammonium acetate was reported. The advantages of this protocol include sh