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An efficient synthesis of 3-vinylpyrroles by Stille coupling reaction of 3-iodopyrroles with vinyltributyltin

โœ Scribed by Jianji Wang; A. Ian Scott


Book ID
103406364
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
148 KB
Volume
36
Category
Article
ISSN
0040-4039

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A facile synthesis of cephem side chains
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Synthesis of 3-vinyl-and 3-alkyl-A3-cephems was performed in a regioselective manner by palladium acetate catalyzed reaction of 3-sulfonato-or 3-bromo-A3-cephems with dialkylzinc or vinyltributyltin. A new access to 3-alkyl-A3-cephems is opened, starting from the allenyl compound 10.