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An efficient synthesis of 3-(N-piperidinemethyl)-2,2,5,5-tetramethyl-1-oxy-3-pyrroline, a promising radioprotector for cancer radiotherapy

✍ Scribed by Wu, Haitao; Coble, Vincent; Vasalatiy, Olga; Swenson, Rolf E.; Krishna, Murali C.; Mitchell, James B.


Book ID
127145972
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
351 KB
Volume
55
Category
Article
ISSN
0040-4039

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## Abstract A series of novel tricyclic __O, N__‐heterocycles, [1, 2, 4]triazolo[3.2‐__d__][1, 5]benzoxazepin‐2‐thiones 7 were achieved via acid‐induced ring closure of the geminal arylazo isothiocyanate compounds 5 which were derived from substituted chroman‐4‐ones. followed by feasible ring expan