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An efficient synthesis and mechanism of formation of 6-acetyl-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid

✍ Scribed by Joseph P. Sanchez


Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
341 KB
Volume
46
Category
Article
ISSN
0040-4020

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## Abstract magnified image A facile approach was developed on assembly of the 2‐pyridone nucleus by ferric chloride promoted [3+3] cycloaddition in propionic acid. The tandem process involves cyclization of Michael adduct followed by aromatization. Thus, different substituted 1,2‐dihydro‐2‐oxo‐3‐