𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An Efficient, Stereospecific Synthesis of the Dimer-Selective Retinoid X Receptor Modulator (2 E ,4 E ,6 Z )-7-[5,6,7,8- Tetrahydro-5,5,8,8-tetramethyl-2- ( n -propyloxy)naphthalen-3-yl]-3- methylocta-2,4,6-trienoic Acid

✍ Scribed by Hamann, Lawrence G.

Book ID
121282718
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
91 KB
Volume
65
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The synthesis of [1′,3′-3H]4-(4′-azido-5
The synthesis of [1′,3′-3H]4-(4′-azido-5′,6′,7′,8′-tetrahydro-5′,5′,8′,8′-tetramethyl-2′-anthracenyl)benzoic acid as a probe of the retinoic acid receptor
✍ Marcia I. Dawson; Peter D. Hobbs; Albert Dorsky; Hiromi Morimoto 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 484 KB

## Abstract The synthesis of [1′,3′‐^3^H]4‐(4′‐azido‐5′,6′,7′,8′‐tetrahydro‐5′,5′,8′,8′‐tetramethyl ‐2′‐anthracenyl)benzoic acid is described. This retinoid was designed as a photoaffinity probe of the receptor sites of cellular retinoic acid‐binding protein and the nuclear retinoic acid receptor p

Syntheses of isotopically labeled 4-[1-(
Syntheses of isotopically labeled 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl]benzoic acid (LGD1069), a potent retinoid x receptor-selective ligand
✍ Lin Zhang; Beth Ann Badea; Debra Enyeart; Elaine M. Berger; Dale E. Mais; Marcus 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 576 KB

## Abstract LGD1069, 4‐[1‐(3,5,5,8,8‐pentamethyl‐5,6,7,8‐tetrahydro‐2‐naphthyl)ethenyl] benzoic acid, is the first retinoid X receptor (RXR) selective retinoid to enter clinical trials for treatment of dermatological diseases and cancer. In order to examine biological properties such as receptor bi