An efficient stereospecific synthesis of olefins by the palladium-catalyzed reaction of grignard reagents with alkenyl iodides.
✍ Scribed by Huu Phuong Dang; Gérard Linstrumelle
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 164 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The reaction of (E)-1-alkenylboronic acids with (Z)-or(E)-1-alkenyl iodides in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium and sodium hydroxide gave the corresponding conjugated (E,E)-or (E,E)--alkadienes with high stereospecificity. Cross-coupling reactions between 1
In the presenceof PdC12(PPb3)2 and Et3N,cbloroenynesandchlorodienesreact rapidly under mild conditions with various Grignard reagents to give isometricallypure conjugated enynes, dienes, dienynesandtrienes in goodisolatedyields. 01997 Publishedby Elsevier Science Ltd.
## Sumnary: The representative (E)-1-alkenyldisiamylboranes and (E)-1-alkenyl-1,3,2-benzodioxaboroles readily obtainable via hydroboration of 1-alkynes react with 1-alkenyl halides or l-alkynyl halides in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium and base to give