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An efficient route to 4-substituted coumarins, 2(5H)-furanones, and pyrones via palladium-catalyzed couplings of alkenyl tosylates with organoindium reagents

✍ Scribed by Wei Gao; Yong Luo; Qiuping Ding; Yiyuan Peng; Jie Wu

Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 581 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.10.096

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✦ Synopsis

Highly efficient palladium-catalyzed couplings of alkenyl tosylates with organoindium reagents under mild conditions are described, which give rise to 4-substituted coumarins, 2(5H)-furanones, and pyrones in good to excellent yields.

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