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An efficient one-pot synthesis of bis-indolylmethanes containing pyrazolyl catalyzed by Brønsted acidic ionic liquid under solvent-free conditions

✍ Scribed by Chenjiang Liu; Chuanji Yu

Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
86 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Brønsted acidic ionic liquid [PyNCH~2~CO~2~H][HSO~4~] was found to be an effective catalyst for the condensation reactions of indoles with various 4‐formylpyrazoles to afford the corresponding bis‐indolylmethanes containing pyrazole under solvent‐free conditions. The satisfactory results were obtained with excellent yields, short reaction time, and simplicity in the experimental procedure. J. Heterocyclic Chem., (2011).

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