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An efficient one pot synthesis of 3-(2-oxo-2H-chromen-3-yl)-6H,8H-pyrimido[4,5-c]pyridazine-5,7-dionesl

✍ Scribed by V. Rajeswar Rao; M. Madan Mohan Reddy

Publisher: Journal of Heterocyclic Chemistry
Year: 2005
Tongue: English
Weight: 31 KB
Volume: 42
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570420631

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✦ Synopsis

An easy, simple and versatile one step synthesis of 3-(2-oxo-2H-chromen-3-yl)-6H,8H-pyrimido[4,5-c]pyridazine-5,7-diones is reported by reaction of 3-acetylcoumarins (1) with alloxan monohydrate (2) in acetic acid followed by hydrazine hydrate.

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