✦ LIBER ✦

An efficient O-dealkylation procedure for the synthesis of (3as,cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl-3,4-dihydro-2(1H)-isoquinolinecarboxylate

✍ Scribed by Zhongli Gao; Thomas B. K. Lee; Barbara S. Rauckman

Publisher: Journal of Heterocyclic Chemistry
Year: 2000
Tongue: English
Weight: 179 KB
Volume: 37
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570370216

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✦ Synopsis

Abstract

The title compound is synthesized in high yields and purity from (‐)‐eserethole (2a) via a lithium bromide catalyzed hydrobromic acid O‐dealkylation procedure as the key step.

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