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An Efficient Modification of the Hofmann Rearrangement: Synthesis of Methyl Carbamates.

โœ Scribed by Pranjal Gogoi; Dilip Konwar


Book ID
102006826
Publisher
John Wiley and Sons
Year
2007
Weight
18 KB
Volume
38
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES


Preparation of methyl carbamates via a m
โœ Xicai Huang; Jeffrey W. Keillor ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 154 KB

Treatment of a series ofpara-substituted aromatic and primary aliphatic carboxamides with NBS and NaOMe in methanol heated to reflux for ten minutes results in the conversion of the carboxamides to their corresponding primary amino methyl carbamates in nearly quantitative yields. The mild oxidative