An efficient method for the resolution of rac-VANOL by molecular complexation with (1S,2S)-(+)-diaminocyclohexane
β Scribed by Zheng, Chen; Chen, Fen-er
- Book ID
- 124087891
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 891 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0957-4166
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Racemic S-methyl-S-phenylsulfoximine (\_)-1 can be resolved with only 0.6 equivalents of (+)-camphorsulfonic acid by avoiding any recrystallization to give (+)-1 of >\_99% ee in 80% yield and (-)-1 of 97-99% ee in 74% yield. This procedure, which is based on the separation of the diastereomeric salt
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A large laboratory scale synthesis of (S)-a-methylphenylalanine from benzaldehyde and methyl cyanoacetate has been developed. The synthesis is based on the following sequence: (i) preparation of racemic 2-cyano-2-methyl-3-phenylpropanoic acid, (ii) resolution of the enantiomers by crystallisation us