✦ LIBER ✦

An efficient method for the preparation of antitumoral α-keto-imines benzyldihydroisoquinolines by selective benzylic oxidation with C/Pd in acetonitrile

✍ Scribed by Inmaculada Andreu; Nuria Cabedo; Ghanem Atassi; Alain Pierre; Daniel H Caignard; Pierre Renard; Diego Cortes; Almudena Bermejo

Book ID: 104232298
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 99 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)02257-2

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✦ Synopsis

A series of potent antitumor a-keto-imine BDHIQ derivatives were synthesized and assayed in vitro against L1210 leukemia cell line. A new and easy method for the direct formation of a-keto-imine from imine BDHIQ's was performed with 10%

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