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An efficient method for cloning human autoantigen-specific T cells

✍ Scribed by Stuart I. Mannering; James A. Dromey; Jessica S. Morris; Daniel J. Thearle; Kent P. Jensen; Leonard C. Harrison

Book ID: 113716947
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 395 KB
Volume: 298
Category: Article
ISSN: 0022-1759
DOI: 10.1016/j.jim.2005.01.001

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## Abstract ## Objective To identify and characterize human T cells reactive with heterogeneous nuclear RNP A2 (hnRNP A2) antigen, and to determine the ability of hnRNP‐reactive T cells to assist in the production of human autoantibodies. ## Methods T cells from patients with high serum levels o