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An Efficient Method for Catalytic Asymmetric Reduction of Diketones and Application of Synthesis to Chiral 2,5-Diphenylpyrrolidine and 2,5-Diphenylthiolane.

✍ Scribed by Xiang Li; Gang Zhao; Wei-Guo Cao


Publisher
John Wiley and Sons
Year
2007
Weight
31 KB
Volume
38
Category
Article
ISSN
0931-7597

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✍ Ben L. Feringa; Ben De Lange πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 765 KB

The synthesis of enantiomerically pure 5-menthyloxy-2(5B)-furanones is described as well as the diastereoselective 1,4-addition of thiols to these butenolides to yield new homochiral CQ-synthons. Kinetic resolution of 5-methoxy-2(5H)-furanone, with an enautiameric excess of 139, wae achieved by cinc