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An Efficient Large-Scale Synthesis of a Naphthylacetic Acid CRTH2 Receptor Antagonist

✍ Scribed by Shu, Lianhe; Wang, Ping; Gu, Chen; Liu, Wen; Alabanza, Lady Mae; Zhang, Yingchao

Book ID
120200641
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
333 KB
Volume
17
Category
Article
ISSN
1083-6160

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✍ Abhishek K. Jain; Veerasamy Ravichandran; Rajesh Singh; Vishnukanth Mourya; Ram πŸ“‚ Article πŸ“… 2009 πŸ› Versita 🌐 English βš– 359 KB

## Abstract In pursuit of better CRTh2 receptor antagonist agents, QSAR studies were performed on a series of 2,4-disubstituted phenoxyacetic acid derivatives. Stepwise multiple linear regression analysis was performed to derive QSAR models which were further evaluated for statistical significance