An efficient diastereoselective synthesis of β-1-formyl-2,3,4,6-tetra-O-benzyl-d-glucopyranoside
✍ Scribed by Frédéric Labéguère; Jean-Pierre Lavergne; Jean Martinez
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 60 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
A diastereoselective synthesis of b-1-formyl-2,3,4,6-tetra-O-benzyl-D-glucopyranoside in four steps, using an umpolung Seebach reaction is described.
📜 SIMILAR VOLUMES
The addition of 2-lithiobenzothiazole to D-gluconolactone followed by deoxygenation of the resulting ketose affords a mixture of benzothiazolyl aand b-D-glucopyranoside; treatment of this mixture with sodium methoxide gives the b-anomer from which the title aldehyde is obtained in a pure form by tra
## Crystals of the tetrasaccharide, (2,3,4,6-tetra-0acetyl-fi-D-ghxopyranosyl~-(1 + 3)-[2,3,4,6-tetra-O-acetyI+LD-gIucopyranosyI-(1 --t 6)]-(2,4-di-0-acetyl-g\_D-glucopyranosyl)-1 --) 3)-1,2,4,6-tetrad-acetyl$?-n-ghicopyranose, belong to tge monoclinic system, space group P2,, with a = 12.709(4),