An efficient approach towards three component coupling of one pot reaction for synthesis of functionalized benzopyrans
โ Scribed by B. Sunil Kumar; N. Srinivasulu; R. H. Udupi; B. Rajitha; Y. Thirupathi Reddy; P. Narsimha Reddy; P. S. Kumar
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2006
- Tongue
- English
- Weight
- 153 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-152X
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โฆ Synopsis
Abstract
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Three component coupling of one pot reaction which servers as the most convenient route to the synthesis of benzopyran derivatives using the TiCl~4~ catalyst (10 mol %) under solvent free conditions is described. The procedure offers a systematic method with a number of advantages including operational simplicity, neat reactions, reduced reaction time, high yields of products and applicability to large scale reactions.
๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
General procedure: A flame-dried round-bottomed flask was charged with 4 (1 equiv) and the olefin cross partner (3.0 equiv). A rubber septum was attached, dichloromethane was added (0.2 ยฑ 0.3 n in 4), and argon was bubbled through the resultant solution for 10 min. Under a stream of argon, 3 (0.050