An efficient and stereoselective synthesis of enantiopure 1,2,7-trihydroxylated pyrrolizidines

✍ Scribed by Javier de Vicente; Ramón Gómez Arrayás; Juan C. Carretero

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 254 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01265-4

✦ Synopsis

An efficient approach to the stereoselective synthesis of enantiopure 1,2,7-trihydroxylated pyrrolizidines from the readily available optically pure y-hydroxy-~,~l-unsaturated sulfone 2a is described.