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An efficient and practical EPC synthesis of β-amino acids from L-asparagine

✍ Scribed by Peter Gmeiner


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
629 KB
Volume
324
Category
Article
ISSN
0365-6233

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Synthesis of optically active α,β-disubs
✍ Gmeiner, Peter ;Hummel, Evi ;Haubmann, Christian 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 695 KB

## Abstract Starting from the enantiomerically pure building block 2 which is readily available from D‐asparagine α,β‐disubstituted β‐amino nitriles and β‐amino acids could be synthesized. After deprotonation of the nitrile α‐position the introduction of substituents was performed by alkylation of