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An efficient and practical direct resolution of racemic 1,1′-bi-2-naphthol to both of its pure enantiomers

✍ Scribed by Qiao-Sheng Hu; Dilrukshi Vitharana; Lin Pu


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
181 KB
Volume
6
Category
Article
ISSN
0957-4166

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A new type of N,P chiral ligand, binaphthyl amino phosphine 1 was synthesized through a simple and practical resolution of racemic 2-amino-2'-hydroxy-1,1'-binaphthyl by molecular complexation with 0.5 equivalents of N-benzylcinchonidium chloride in the solid state. The present procedure represents t